A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

Some individuals develop antibodies against the polyethylene glycol that is commonly used in therapeutic preparations. Here the authors conduct a GWAS in Han Chinese and find the IGH locus is associated with anti-PEG IgM.

Bibliographic Details
Main Authors: Chia-Jung Chang, Chien-Hsiun Chen, Bing-Mae Chen, Yu-Cheng Su, Ying-Ting Chen, Michael S. Hershfield, Ming-Ta Michael Lee, Tian-Lu Cheng, Yuan-Tsong Chen, Steve R. Roffler, Jer-Yuarn Wu
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00622-4

Internet

https://doi.org/10.1038/s41467-017-00622-4

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