Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo

Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo

IntroductionThe effects of bacterial infections on the response to subsequent viral infections are largely unknown. This is important to elucidate to increase insight into the pathophysiology of bacterial and viral co-infections, and to assess whether bacterial infections may influence the course of...

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Bibliographic Details
Main Authors: Rebecca M. Koch, Matthijs Kox, Eleonora J. M. Thijs, Janette C. Rahamat-Langendoen, Frank L. van de Veerdonk, Jelle Gerretsen, Joyce Schloesser, Dimitri Diavatopoulos, Guus F. Rimmelzwaan, Mihai G. Netea, Johannes G. van der Hoeven, Marien I. de Jonge, Peter Pickkers
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
sepsis
lipopolysaccharide
endotoxin tolerance
influenza
live-attenuated quadrivalent influenza vaccine
Fluenz
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01600/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01600/full

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