Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL

Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL

Juvenile myelomonocytic leukemia (JMML) is a rare myeloproliferative disorder of early childhood characterized by expansion of clonal myelomonocytic cells and hyperactive Ras/MAPK signaling. The disorder is caused by somatic and/or germline mutations in genes involved in the Ras/MAPK and JAK/STAT si...

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Bibliographic Details
Main Authors: Alyssa L. Gagne, Jean Ann Maguire, Shilpa Gandre-Babbe, Stella T. Chou, Sarah K. Tasian, Mignon L. Loh, Mitchell J. Weiss, Paul Gadue, Deborah L. French
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118301697

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http://www.sciencedirect.com/science/article/pii/S1873506118301697

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