The NMDA receptor co-agonists, d-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex

The NMDA receptor co-agonists, d-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex

There is substantial evidence, both pharmacological and genetic, that hypofunction of the N-methyl-d-aspartate receptor (NMDAR) is a core pathophysiological feature of schizophrenia. There are morphological brain changes associated with schizophrenia, including perturbations in the dendritic morphol...

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Bibliographic Details
Main Authors: Darrick T. Balu, Alo C. Basu, John P. Corradi, Angela M. Cacace, Joseph T. Coyle
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Neurobiology of Disease
Subjects:
Serine racemase
Glycine
NMDA receptor
Somatosensory cortex
BDNF
Dendritic spines
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611100338X

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http://www.sciencedirect.com/science/article/pii/S096999611100338X

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