Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology

Conductance in voltage-gated ion channels is regulated by membrane voltage through structural domains known as voltage sensors. A single structural class of voltage sensor domain exists, but two different modes of voltage sensor attachment to the pore occur in nature: domain-swapped and non-domain-s...

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Bibliographic Details
Main Authors: Xiao Tao, Roderick MacKinnon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-11-01
Series:eLife
Subjects:
VSD
Online Access:https://elifesciences.org/articles/52164