High resolution detection and analysis of CpG dinucleotides methylation using MBD-Seq technology.

High resolution detection and analysis of CpG dinucleotides methylation using MBD-Seq technology.

Methyl-CpG binding domain protein sequencing (MBD-seq) is widely used to survey DNA methylation patterns. However, the optimal experimental parameters for MBD-seq remain unclear and the data analysis remains challenging. In this study, we generated high depth MBD-seq data in MCF-7 cell and developed...

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Bibliographic Details
Main Authors: Xun Lan, Christopher Adams, Mark Landers, Miroslav Dudas, Daniel Krissinger, George Marnellos, Russell Bonneville, Maoxiong Xu, Junbai Wang, Tim H-M Huang, Gavin Meredith, Victor X Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3136941?pdf=render

Internet

http://europepmc.org/articles/PMC3136941?pdf=render

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