Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release

Gliomas arise in the glial cells of the brain or spine and are the most prevalent and devastating type of brain tumors. Studies of tumor immunology have established the importance of the tumor micro-environment as a driver of oncogenesis. Inflammatory mediators such as IL-1β and IL-18 released by mo...

Full description

Bibliographic Details
Main Authors: Lei Tong, Chuncheng Xie, Yafen Wei, Yunyue Qu, Hongsheng Liang, Yiwei Zhang, Tianye Xu, Xin Qian, Huijia Qiu, Haoyu Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
EMT
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00364/full