Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16

Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16

Though human rhinoviruses (HRVs) are usually innocuous viruses, they can trigger serious consequences in certain individuals, especially in the setting of impaired interferon (IFN) synthesis. Plasmacytoid dendritic cells (pDCs) are key IFN producing cells, though we know little about the role of pDC...

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Bibliographic Details
Main Authors: Yang Xi, Niamh M. Troy, Denise Anderson, Olga M. Pena, Jason P. Lynch, Simon Phipps, Anthony Bosco, John W. Upham
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
plasmacytoid dendritic cells
human rhinovirus
human rhinovirus responsive genes
plasmacytoid dendritic cell-dependent gene expression
innate immune response
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01351/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01351/full

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