Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome

Abstract Background Studies of the cystic fibrosis (CF) lung microbiome have consistently shown that lung function decline is associated with decreased microbial diversity due to the dominance of opportunistic pathogens. However, how this phenomenon is reflected in the metabolites and chemical envir...

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Bibliographic Details
Main Authors: Robert A. Quinn, Sandeep Adem, Robert H. Mills, William Comstock, Lindsay DeRight Goldasich, Gregory Humphrey, Alexander A. Aksenov, Alexei V. Melnik, Ricardo da Silva, Gail Ackermann, Nuno Bandeira, David J. Gonzalez, Doug Conrad, Anthony J. O’Donoghue, Rob Knight, Pieter C. Dorrestein
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Microbiome
Online Access:http://link.springer.com/article/10.1186/s40168-019-0636-3