An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

Abstract Background Novel theranostic options for high-risk non-muscle invasive bladder cancer are urgently needed. This requires a thorough evaluation of experimental approaches in animal models best possibly reflecting human disease before entering clinical studies. Although several bladder cancer...

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Bibliographic Details
Main Authors: Doreen Huebner, Christiane Rieger, Ralf Bergmann, Martin Ullrich, Sebastian Meister, Marieta Toma, Ralf Wiedemuth, Achim Temme, Vladimir Novotny, Manfred P. Wirth, Michael Bachmann, Jens Pietzsch, Susanne Fuessel
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Subjects:
Bioluminescence
Luciferase
Orthotopic xenograft models
Small animal multimodal imaging
Magnetic resonance imaging
Optical imaging
Online Access:http://link.springer.com/article/10.1186/s12885-017-3778-3

Internet

http://link.springer.com/article/10.1186/s12885-017-3778-3

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