A 3.7 Mb deletion encompassing ZEB2 causes a novel polled and multisystemic syndrome in the progeny of a somatic mosaic bull.

A 3.7 Mb deletion encompassing ZEB2 causes a novel polled and multisystemic syndrome in the progeny of a somatic mosaic bull.

Polled and Multisystemic Syndrome (PMS) is a novel developmental disorder occurring in the progeny of a single bull. Its clinical spectrum includes polledness (complete agenesis of horns), facial dysmorphism, growth delay, chronic diarrhea, premature ovarian failure, and variable neurological and ca...

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Bibliographic Details
Main Authors: Aurélien Capitan, Aurélie Allais-Bonnet, Alain Pinton, Brigitte Marquant-Le Guienne, Daniel Le Bourhis, Cécile Grohs, Stéphan Bouet, Laëtitia Clément, Laura Salas-Cortes, Eric Venot, Stéphane Chaffaux, Bernard Weiss, Arnaud Delpeuch, Guy Noé, Marie-Noëlle Rossignol, Sarah Barbey, Dominique Dozias, Emilie Cobo, Harmonie Barasc, Aurélie Auguste, Maëlle Pannetier, Marie-Christine Deloche, Emeline Lhuilier, Olivier Bouchez, Diane Esquerré, Gérald Salin, Christophe Klopp, Cécile Donnadieu, Céline Chantry-Darmon, Hélène Hayes, Yves Gallard, Claire Ponsart, Didier Boichard, Eric Pailhoux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3494662?pdf=render

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http://europepmc.org/articles/PMC3494662?pdf=render

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