Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus.

The phosphoinositide-3 kinase (PI3K) pathway regulates diverse cellular activities related to cell growth, migration, survival, and vesicular trafficking. It is known that Ebola virus requires endocytosis to establish an infection. However, the cellular signals that mediate this uptake were unknown...

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Bibliographic Details
Main Authors: Mohammad F Saeed, Andrey A Kolokoltsov, Alexander N Freiberg, Michael R Holbrook, Robert A Davey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2516934?pdf=render