Innate signalling molecules as genetic adjuvants do not alter the efficacy of a DNA-based influenza A vaccine.

In respect to the heterogeneity among influenza A virus strains and the shortcomings of current vaccination programs, there is a huge interest in the development of alternative vaccines that provide a broader and more long-lasting protection. Gene-based approaches are considered as promising candida...

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Bibliographic Details
Main Authors: Dennis Lapuente, Viktoria Stab, Michael Storcksdieck Genannt Bonsmann, Andre Maaske, Mario Köster, Han Xiao, Christina Ehrhardt, Matthias Tenbusch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231138