Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation

Summary: Lipid droplets, which store triglycerides and cholesterol esters, are a prominent feature of clear cell renal cell carcinoma (ccRCC). Although their presence in ccRCC is critical for sustained tumorigenesis, their contribution to lipid homeostasis and tumor cell viability is incompletely un...

Full description

Bibliographic Details
Main Authors: Daniel Ackerman, Sergey Tumanov, Bo Qiu, Evdokia Michalopoulou, Michelle Spata, Andrew Azzam, Hong Xie, M. Celeste Simon, Jurre J. Kamphorst
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718312695