The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy
Pathological left ventricular hypertrophy (LVH) occurs in response to pressure overload and remains the single most important clinical predictor of cardiac mortality. The molecular pathways in the induction of pressure overload LVH are potential targets for therapeutic intervention. Current treatmen...
Main Authors: | Yang Guo, Ze-Yan Yu, Jianxin Wu, Hutao Gong, Scott Kesteven, Siiri E Iismaa, Andrea Y Chan, Sara Holman, Silvia Pinto, Andy Pironet, Charles D Cox, Robert M Graham, Rudi Vennekens, Michael P Feneley, Boris Martinac |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/66582 |
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