Detection of IGF2BP3, HOXB7, and NEK2 mRNA expression in brush cytology specimens as a new diagnostic tool in patients with biliary strictures.

Detection of IGF2BP3, HOXB7, and NEK2 mRNA expression in brush cytology specimens as a new diagnostic tool in patients with biliary strictures.

It is a challenging task to distinguish between benign and malignant lesions in patients with biliary strictures. Here we analyze whether determination of target gene mRNA levels in intraductal brush cytology specimens may be used to improve the diagnosis of bile duct carcinoma.Brush cytology specim...

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Bibliographic Details
Main Authors: Hans Dieter Nischalke, Volker Schmitz, Carolin Luda, Katharina Aldenhoff, Cordula Berger, Georg Feldmann, Tilman Sauerbruch, Ulrich Spengler, Jacob Nattermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3413695?pdf=render

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http://europepmc.org/articles/PMC3413695?pdf=render

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