Impact of Interferon-α Receptor-1 Promoter Polymorphisms on the Transcriptome of the Hepatitis B Virus-Associated Hepatocellular Carcinoma

Impact of Interferon-α Receptor-1 Promoter Polymorphisms on the Transcriptome of the Hepatitis B Virus-Associated Hepatocellular Carcinoma

Background and aimsGenetic polymorphisms within the promoter of interferon-α receptor type-1 (IFNAR1) have been associated with the susceptibility to and the outcome of chronic hepatitis B virus (HBV) infection. However, the impact of these polymorphisms in the transcriptome of the HBV-associated he...

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Bibliographic Details
Main Authors: Timokratis Karamitros, George Papatheodoridis, Dimitrios Paraskevis, Angelos Hatzakis, Jean L. Mbisa, Urania Georgopoulou, Paul Klenerman, Gkikas Magiorkinis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
hepatitis virus B
interferon-α receptor type-1 promoter
hepatocellular carcinoma
interferon-α receptor
polymorphism
transcriptome
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00777/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00777/full

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