Raman Spectroscopy and Machine Learning for IDH Genotyping of Unprocessed Glioma Biopsies

Isocitrate dehydrogenase (IDH) mutational status is pivotal in the management of gliomas. Patients with IDH-mutated (IDH-MUT) tumors have a better prognosis and benefit more from extended surgical resection than IDH wild-type (IDH-WT). Raman spectroscopy (RS) is a minimally invasive optical techniqu...

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Bibliographic Details
Main Authors: Tommaso Sciortino, Riccardo Secoli, Ester d’Amico, Sara Moccia, Marco Conti Nibali, Lorenzo Gay, Marco Rossi, Nicolò Pecco, Antonella Castellano, Elena De Momi, Bethania Fernandes, Marco Riva, Lorenzo Bello
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/16/4196