Raman Spectroscopy and Machine Learning for IDH Genotyping of Unprocessed Glioma Biopsies

Raman Spectroscopy and Machine Learning for IDH Genotyping of Unprocessed Glioma Biopsies

Isocitrate dehydrogenase (IDH) mutational status is pivotal in the management of gliomas. Patients with IDH-mutated (IDH-MUT) tumors have a better prognosis and benefit more from extended surgical resection than IDH wild-type (IDH-WT). Raman spectroscopy (RS) is a minimally invasive optical techniqu...

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Bibliographic Details
Main Authors: Tommaso Sciortino, Riccardo Secoli, Ester d’Amico, Sara Moccia, Marco Conti Nibali, Lorenzo Gay, Marco Rossi, Nicolò Pecco, Antonella Castellano, Elena De Momi, Bethania Fernandes, Marco Riva, Lorenzo Bello
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
raman spectroscopy
neuro-oncology
classification
glioma
machine learning
isocitrate dehydrogenase (IDH)
Online Access:https://www.mdpi.com/2072-6694/13/16/4196

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