Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis.

Clinicopathological studies suggest that Alzheimer's disease (AD) pathology begins ∼10-15 years before the resulting cognitive impairment draws medical attention. Biomarkers that can detect AD pathology in its early stages and predict dementia onset would, therefore, be invaluable for patient c...

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Bibliographic Details
Main Authors: Rebecca Craig-Schapiro, Max Kuhn, Chengjie Xiong, Eve H Pickering, Jingxia Liu, Thomas P Misko, Richard J Perrin, Kelly R Bales, Holly Soares, Anne M Fagan, David M Holtzman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3079734?pdf=render