Autosomal dominant Alzheimer disease: A unique resource to study CSF biomarker changes in preclinical AD

by Suzanne Elizabeth Schindler, Anne M Fagan
Published 2015-06-01

Biomarkers of Alzheimer's disease

by Rebecca Craig-Schapiro, Anne M. Fagan, David M. Holtzman
Published 2009-08-01

Diurnal oscillation of CSF Aβ and other AD biomarkers

by Brendan P. Lucey, Anne M. Fagan, David M. Holtzman, John C. Morris, Randall J. Bateman
Published 2017-05-01

Human and Murine ApoE Markedly Alters Aβ Metabolism before and after Plaque Formation in a Mouse Model of Alzheimer's Disease

by Anne M. Fagan, Melanie Watson, Maia Parsadanian, Kelly R. Bales, Steven M. Paul, David M. Holtzman
Published 2002-04-01

GPS driving: a digital biomarker for preclinical Alzheimer disease

by Sayeh Bayat, Ganesh M. Babulal, Suzanne E. Schindler, Anne M. Fagan, John C. Morris, Alex Mihailidis, Catherine M. Roe
Published 2021-06-01

Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease

by Richard E. Hartman, Aartie Shah, Anne M. Fagan, Katherine E. Schwetye, Maia Parsadanian, Risa N. Schulman, Mary Beth Finn, David M. Holtzman
Published 2006-12-01

Quantitative label-free proteomics for discovery of biomarkers in cerebrospinal fluid: assessment of technical and inter-individual variation.

by Richard J Perrin, Jacqueline E Payton, James P Malone, Petra Gilmore, Alan E Davis, Chengjie Xiong, Anne M Fagan, R Reid Townsend, David M Holtzman
Published 2013-01-01

Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis.

by Rebecca Craig-Schapiro, Max Kuhn, Chengjie Xiong, Eve H Pickering, Jingxia Liu, Thomas P Misko, Richard J Perrin, Kelly R Bales, Holly Soares, Anne M Fagan, David M Holtzman
Published 2011-04-01

Using the A/T/N Framework to Examine Driving in Preclinical Alzheimer’s Disease

by Catherine M. Roe, Ganesh M. Babulal, Sarah H. Stout, David B. Carr, Monique M. Williams, Tammie L. S. Benzinger, Anne M. Fagan, David M. Holtzman, Beau M. Ances, John C. Morris
Published 2018-05-01

Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome

by Rachel L. Henson, Eric Doran, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, Florence Lai, Joseph H. Lee, H. Diana Rosas, Nicole Schupf, Shahid H. Zaman, Ira T. Lott, Anne M. Fagan
Published 2020-01-01

Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.

by John S K Kauwe, Carlos Cruchaga, Celeste M Karch, Brooke Sadler, Mo Lee, Kevin Mayo, Wayne Latu, Manti Su'a, Anne M Fagan, David M Holtzman, John C Morris, Alzheimer's Disease Neuroimaging Initiative, Alison M Goate
Published 2011-02-01

Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-β

by Masayuki Morikawa, John D. Fryer, Patrick M. Sullivan, Erin A. Christopher, Suzanne E. Wahrle, Ronald B. DeMattos, Mark A. O'Dell, Anne M. Fagan, Hilal A. Lashuel, Thomas Walz, Kiyofumi Asai, David M. Holtzman
Published 2005-06-01

Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer’s disease

by Umesh Gangishetti, J. Christina Howell, Richard J. Perrin, Natalia Louneva, Kelly D. Watts, Alexander Kollhoff, Murray Grossman, David A. Wolk, Leslie M. Shaw, John C. Morris, John Q. Trojanowski, Anne M. Fagan, Steven E. Arnold, William T. Hu
Published 2018-09-01

Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease

by Qing Wang, Yong Wang, Jingxia Liu, Courtney L. Sutphen, Carlos Cruchaga, Tyler Blazey, Brian A. Gordon, Yi Su, Charlie Chen, Joshua S. Shimony, Beau M. Ances, Nigel J. Cairns, Anne M. Fagan, John C. Morris, Tammie L.S. Benzinger
Published 2019-01-01

Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease.

by Richard J Perrin, Rebecca Craig-Schapiro, James P Malone, Aarti R Shah, Petra Gilmore, Alan E Davis, Catherine M Roe, Elaine R Peskind, Ge Li, Douglas R Galasko, Christopher M Clark, Joseph F Quinn, Jeffrey A Kaye, John C Morris, David M Holtzman, R Reid Townsend, Anne M Fagan
Published 2011-01-01

The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.

by Bruno A Benitez, Celeste M Karch, Yefei Cai, Sheng Chih Jin, Breanna Cooper, David Carrell, Sarah Bertelsen, Lori Chibnik, Julie A Schneider, David A Bennett, Alzheimer's Disease Neuroimaging Initiative, Genetic and Environmental Risk for Alzheimer's Disease Consortium GERAD, Anne M Fagan, David Holtzman, John C Morris, Alison M Goate, Carlos Cruchaga
Published 2013-01-01

Discovery and validation of autosomal dominant Alzheimer’s disease mutations

by Simon Hsu, Brian A. Gordon, Russ Hornbeck, Joanne B. Norton, Denise Levitch, Adia Louden, Ellen Ziegemeier, Robert Laforce, Jasmeer Chhatwal, Gregory S. Day, Eric McDade, John C. Morris, Anne M. Fagan, Tammie L. S. Benzinger, Alison M. Goate, Carlos Cruchaga, Randall J. Bateman, Dominantly Inherited Alzheimer Network (DIAN), Celeste M. Karch
Published 2018-07-01

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.

by John S K Kauwe, Matthew H Bailey, Perry G Ridge, Rachel Perry, Mark E Wadsworth, Kaitlyn L Hoyt, Lyndsay A Staley, Celeste M Karch, Oscar Harari, Carlos Cruchaga, Benjamin J Ainscough, Kelly Bales, Eve H Pickering, Sarah Bertelsen, Alzheimer's Disease Neuroimaging Initiative, Anne M Fagan, David M Holtzman, John C Morris, Alison M Goate
Published 2014-10-01

SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease.

by Carlos Cruchaga, John S K Kauwe, Kevin Mayo, Noah Spiegel, Sarah Bertelsen, Petra Nowotny, Aarti R Shah, Richard Abraham, Paul Hollingworth, Denise Harold, Michael M Owen, Julie Williams, Simon Lovestone, Elaine R Peskind, Ge Li, James B Leverenz, Douglas Galasko, Alzheimer's Disease Neuroimaging Initiative, John C Morris, Anne M Fagan, David M Holtzman, Alison M Goate
Published 2010-09-01

Relationships between big‐five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease

by Andrew J. Aschenbrenner, Jennifer Petros, Eric McDade, Guoqiao Wang, David A. Balota, Tammie LS Benzinger, Carlos Cruchaga, Alison Goate, Chengjie Xiong, Richard Perrin, Anne M. Fagan, Neill Graff‐Radford, Bernardino Ghetti, Johannes Levin, Endy Weidinger, Peter Schofield, Susanne Gräber, Jae‐Hong Lee, Jasmeer P. Chhatwal, John C. Morris, Randall Bateman, Jason Hassenstab, for the Dominantly Inherited Alzheimer Network
Published 2020-01-01