Mitochondrial DNA in CSF distinguishes LRRK2 from idiopathic Parkinson's disease

by Petar Podlesniy, Dolores Vilas, Peggy Taylor, Leslie M. Shaw, Eduard Tolosa, Ramon Trullas
Published 2016-10-01

Insulin Receptor Substrate-1 (IRS-1) and IRS-2 expression levels are associated with prognosis in non-small cell lung cancer (NSCLC).

by Andrew J Piper, Jennifer L Clark, Jose Mercado-Matos, Asia N Matthew-Onabanjo, Chung-Cheng Hsieh, Ali Akalin, Leslie M Shaw
Published 2019-01-01

Normalization of CSF pTau measurement by Aβ40 improves its performance as a biomarker of Alzheimer’s disease

by Tengfei Guo, Deniz Korman, Renaud La Joie, Leslie M. Shaw, John Q. Trojanowski, William J. Jagust, Susan M. Landau, for the Alzheimer’s Disease Neuroimaging Initiative
Published 2020-08-01

Detection of Alzheimer’s disease (AD) specific tau pathology with conformation-selective anti-tau monoclonal antibody in co-morbid frontotemporal lobar degeneration-tau (FTLD-tau)...

by Garrett S. Gibbons, Soo-Jung Kim, John L. Robinson, Lakshmi Changolkar, David J. Irwin, Leslie M. Shaw, Virginia M.-Y. Lee, John Q. Trojanowski
Published 2019-03-01

The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease.

by Bianca A Trombetta, Becky C Carlyle, Aaron M Koenig, Leslie M Shaw, John Q Trojanowski, David A Wolk, Joseph J Locascio, Steven E Arnold
Published 2018-01-01

Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI.

by Jon B Toledo, Xiao Da, Priyanka Bhatt, David A Wolk, Steven E Arnold, Leslie M Shaw, John Q Trojanowski, Christos Davatzikos, Alzheimer’s Disease Neuroimaging Initiative
Published 2013-01-01

Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells

by Hira Lal Goel, Tatiana Gritsko, Bryan Pursell, Cheng Chang, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Leslie M. Shaw, Arthur M. Mercurio
Published 2014-05-01

Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer.

by Marc A Becker, Yasir H Ibrahim, Annabell S Oh, Dedra H Fagan, Sara A Byron, Aaron L Sarver, Adrian V Lee, Leslie M Shaw, Cheng Fan, Charles M Perou, Douglas Yee
Published 2016-01-01

An Alzheimer's Disease-Derived Biomarker Signature Identifies Parkinson's Disease Patients with Dementia.

by Yosef Berlyand, Daniel Weintraub, Sharon X Xie, Ian A Mellis, Jimit Doshi, Jacqueline Rick, Jennifer McBride, Christos Davatzikos, Leslie M Shaw, Howard Hurtig, John Q Trojanowski, Alice S Chen-Plotkin
Published 2016-01-01

Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease

by Christopher A Brown, Nathan F Johnson, Amelia J Anderson-Mooney, Gregory A Jicha, Leslie M Shaw, John Q Trojanowski, Linda J Van Eldik, Frederick A Schmitt, Charles D Smith, Brian T Gold
Published 2017-01-01

Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative

by Brice Laurens, Radu Constantinescu, Roy Freeman, Alexander Gerhard, Kurt Jellinger, Andreas Jeromin, Florian Krismer, Brit Mollenhauer, Michael G. Schlossmacher, Leslie M. Shaw, Marcel M. Verbeek, Gregor K. Wenning, Kristian Winge, Jing Zhang, Wassilios G. Meissner
Published 2015-08-01

Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer’s disease

by Umesh Gangishetti, J. Christina Howell, Richard J. Perrin, Natalia Louneva, Kelly D. Watts, Alexander Kollhoff, Murray Grossman, David A. Wolk, Leslie M. Shaw, John C. Morris, John Q. Trojanowski, Anne M. Fagan, Steven E. Arnold, William T. Hu
Published 2018-09-01

Derivation of cutoffs for the Elecsys® amyloid β (1–42) assay in Alzheimer's disease

by Leslie M. Shaw, Teresa Waligorska, Leona Fields, Magdalena Korecka, Michal Figurski, John Q. Trojanowski, Udo Eichenlaub, Simone Wahl, Marian Quan, Michael J. Pontecorvo, D. Richard Lachno, Jayne A. Talbot, Scott W. Andersen, Eric R. Siemers, Robert A. Dean
Published 2018-01-01

Alzheimer’s cerebrospinal biomarkers from Lumipulse fully automated immunoassay: concordance with amyloid-beta PET and manual immunoassay in Koreans

by Sohee Moon, Sujin Kim, Sakulrat Mankhong, Seong Hye Choi, Manu Vandijck, Vesna Kostanjevecki, Jee Hyang Jeong, Soo Jin Yoon, Kyung Won Park, Eun-Joo Kim, Bora Yoon, Hee Jin Kim, Jae-Won Jang, Jin Yong Hong, Dong-Ho Park, Leslie M. Shaw, Ju-Hee Kang
Published 2021-01-01

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

by Kwangsik Nho, Sungeun Kim, Emrin Horgusluoglu, Shannon L. Risacher, Li Shen, Dokyoon Kim, Seunggeun Lee, Tatiana Foroud, Leslie M. Shaw, John Q. Trojanowski, Paul S. Aisen, Ronald C. Petersen, Clifford R. Jack, Michael W. Weiner, Robert C. Green, Arthur W. Toga, Andrew J. Saykin, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published 2017-05-01

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

by Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Kai Schlepckow, Miguel Ángel Araque Caballero, Nicolai Franzmeier, Anja Capell, Katrin Fellerer, Brigitte Nuscher, Erden Eren, Johannes Levin, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Leslie M. Shaw, John Q. Trojanowski, Michael Weiner, Michael Ewers, Christian Haass, for the Alzheimer’s Disease Neuroimaging Initiative
Published 2019-01-01

Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel.

by Sungeun Kim, Shanker Swaminathan, Mark Inlow, Shannon L Risacher, Kwangsik Nho, Li Shen, Tatiana M Foroud, Ronald C Petersen, Paul S Aisen, Holly Soares, Jon B Toledo, Leslie M Shaw, John Q Trojanowski, Michael W Weiner, Brenna C McDonald, Martin R Farlow, Bernardino Ghetti, Andrew J Saykin, Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published 2013-01-01

The Role of Apolipoprotein E (APOE) Genotype in Early Mild Cognitive Impairment (E-MCI)

by Shannon L Risacher, Sungeun eKim, Sungeun eKim, Li eShen, Li eShen, Kwangsik eNho, Tatiana eForoud, Robert C Green, Ronald C Petersen, Clifford R Jack, Paul S Aisen, Robert A Koeppe, William J Jagust, Leslie M Shaw, John Q Trojanowski, Michael W Weiner, Michael W Weiner, Andrew J Saykin
Published 2013-04-01

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

by Marc Suárez‐Calvet, Anja Capell, Miguel Ángel Araque Caballero, Estrella Morenas‐Rodríguez, Katrin Fellerer, Nicolai Franzmeier, Gernot Kleinberger, Erden Eren, Yuetiva Deming, Laura Piccio, Celeste M Karch, Carlos Cruchaga, Katrina Paumier, Randall J Bateman, Anne M Fagan, John C Morris, Johannes Levin, Adrian Danek, Mathias Jucker, Colin L Masters, Martin N Rossor, John M Ringman, Leslie M Shaw, John Q Trojanowski, Michael Weiner, Michael Ewers, Christian Haass, the Dominantly Inherited Alzheimer Network, the Alzheimer's Disease Neuroimaging Initiative
Published 2018-12-01

Identifying amyloid pathology–related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study

by Yuk Yee Leung, Jon B. Toledo, Alexey Nefedov, Robi Polikar, Nandini Raghavan, Sharon X. Xie, Michael Farnum, Tim Schultz, Young Baek, Vivianna M. Van Deerlin, William T. Hu, David M. Holtzman, Anne M. Fagan, Richard J. Perrin, Murray Grossman, Holly D. Soares, Mitchel A. Kling, Matthew Mailman, Steven E. Arnold, Vaibhav A. Narayan, Virginia M‐Y. Lee, Leslie M. Shaw, David Baker, Gayle M. Wittenberg, John Q. Trojanowski, Li‐San Wang, Alzheimer's Disease Neuroimaging Initiative
Published 2015-09-01