Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation

Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation

Human cytomegalovirus (HCMV) infection is not cleared by the initial immune response but persists for the lifetime of the host, in part due to its ability to establish a latent infection in cells of the myeloid lineage. HCMV has been shown to manipulate the secretion of cellular proteins during both...

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Bibliographic Details
Main Authors: Sarah E. Jackson, Kevin C. Chen, Ian J. Groves, George X. Sedikides, Amar Gandhi, Charlotte J. Houldcroft, Emma L. Poole, Inmaculada Montanuy, Gavin M. Mason, Georgina Okecha, Matthew B. Reeves, John H. Sinclair, Mark R. Wills
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
human cytomegalovirus
latency
monocytes
reactivation
CD4+ T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.657945/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.657945/full

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