Molecular basis of sidekick-mediated cell-cell adhesion and specificity

Molecular basis of sidekick-mediated cell-cell adhesion and specificity

Sidekick (Sdk) 1 and 2 are related immunoglobulin superfamily cell adhesion proteins required for appropriate synaptic connections between specific subtypes of retinal neurons. Sdks mediate cell-cell adhesion with homophilic specificity that underlies their neuronal targeting function. Here we repor...

Full description

Bibliographic Details
Main Authors: Kerry M Goodman, Masahito Yamagata, Xiangshu Jin, Seetha Mannepalli, Phinikoula S Katsamba, Göran Ahlsén, Alina P Sergeeva, Barry Honig, Joshua R Sanes, Lawrence Shapiro
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
cell adhesion
crystal structure
homophilic specificity
neural patterning
synaptic targeting
Online Access:https://elifesciences.org/articles/19058

Internet

https://elifesciences.org/articles/19058

Similar Items