UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

Induction or selection of radioresistant cancer (stem) cells following standard radiotherapy is presumably one of the major causes for recurrence of metastatic disease. One possibility to prevent tumor relapse is the application of targeted immunotherapies including, e.g., chimeric antigen receptor...

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Bibliographic Details
Main Authors: Claudia Arndt, Liliana R. Loureiro, Anja Feldmann, Justyna Jureczek, Ralf Bergmann, Domokos Máthé, Nikolett Hegedüs, Nicole Berndt, Stefanie Koristka, Nicola Mitwasi, Frederick Fasslrinner, Chris Lamprecht, Alexandra Kegler, Anja Hoffmann, Tabea Bartsch, Ayşe Sedef Köseer, Gary Egan, Marc Schmitz, Vaclav Hořejší, Mechthild Krause, Anna Dubrovska, Michael Bachmann
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
radioresistance
cd98
egfr
adaptor car
t cell immunotherapy
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1743036

Internet

http://dx.doi.org/10.1080/2162402X.2020.1743036

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