Macrophage phenotypic switch orchestrates the inflammation and repair/regeneration following acute pancreatitis injury

Background: Impaired or hyperactive pancreas regeneration after injury would cause exocrine insufficiency or recurrent / chronic pancreatitis and potentially carcinogenesis. Macrophages are the most abundant immune cells in the regenerative pancreas, however their phenotype and role remain poorly de...

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Bibliographic Details
Main Authors: Jinghua Wu, Li Zhang, Juanjuan Shi, Ruizhe He, Wenjuan Yang, Aida Habtezion, Ningning Niu, Ping Lu, Jing Xue
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302954