YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias

Abstract Background YKL-40 (also known as Chitinase 3-like 1) is a glycoprotein produced by inflammatory, cancer and stem cells. Its physiological role is not completely understood but YKL-40 is elevated in the brain and cerebrospinal fluid (CSF) in several neurological and neurodegenerative disease...

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Main Authors: Franc Llorens, Katrin Thüne, Waqas Tahir, Eirini Kanata, Daniela Diaz-Lucena, Konstantinos Xanthopoulos, Eleni Kovatsi, Catharina Pleschka, Paula Garcia-Esparcia, Matthias Schmitz, Duru Ozbay, Susana Correia, Ângela Correia, Ira Milosevic, Olivier Andréoletti, Natalia Fernández-Borges, Ina M. Vorberg, Markus Glatzel, Theodoros Sklaviadis, Juan Maria Torres, Susanne Krasemann, Raquel Sánchez-Valle, Isidro Ferrer, Inga Zerr
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Molecular Neurodegeneration
Subjects:
Chitinase 3-like 1
YKL-40
Neuroinflammation
Cerebrospinal fluid
Neurodegenerative dementias
Brain
Online Access:http://link.springer.com/article/10.1186/s13024-017-0226-4

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http://link.springer.com/article/10.1186/s13024-017-0226-4

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