Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

The persistence of replication-competent HIV reservoirs in people living with HIV (PLWH) receiving antiretroviral therapy (ART) is a barrier to cure. Therefore, their accurate quantification is essential for evaluating the efficacy of new therapeutic interventions and orienting the decision to inter...

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Bibliographic Details
Main Authors: Yuwei Zhang, Delphine Planas, Laurence Raymond Marchand, Marta Massanella, Huicheng Chen, Vanessa Sue Wacleche, Annie Gosselin, Jean-Philippe Goulet, Mario Filion, Jean-Pierre Routy, Nicolas Chomont, Petronela Ancuta
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
memory CD4+ T-cells
ART
HIV-1 reservoirs
ATRA
QVOAs
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00902/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00902/full

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