In Vitro Infection with Hepatitis B Virus Using Differentiated Human Serum Culture of Huh7.5-NTCP Cells without Requiring Dimethyl Sulfoxide

In Vitro Infection with Hepatitis B Virus Using Differentiated Human Serum Culture of Huh7.5-NTCP Cells without Requiring Dimethyl Sulfoxide

An estimated two billion people worldwide have been infected with hepatitis B virus (HBV). Despite the high infectivity of HBV in vivo, a lack of easily infectable in vitro culture systems hinders studies of HBV. Overexpression of the sodium taurocholate co-transporting polypeptide (NTCP) bile acid...

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Bibliographic Details
Main Authors: Connie Le, Reshma Sirajee, Rineke Steenbergen, Michael A. Joyce, William R. Addison, D. Lorne Tyrrell
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
hepatitis B virus (HBV)
hepatoma cell culture
sodium taurocholate co-transporting polypeptide (NTCP)
differentiated Huh7.5-NTCP human serum culture
dimethyl sulfoxide (DMSO)
Online Access:https://www.mdpi.com/1999-4915/13/1/97

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https://www.mdpi.com/1999-4915/13/1/97

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