Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the mouse blastocyst is determined by position-dependent Hippo signaling. However, the window of responsiveness to Hippo signaling, the exact timing of lineage commitment and the overall relationship between cell commitment...

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Bibliographic Details
Main Authors: Eszter Posfai, Sophie Petropoulos, Flavia Regina Oliveira de Barros, John Paul Schell, Igor Jurisica, Rickard Sandberg, Fredrik Lanner, Janet Rossant
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-02-01
Series:eLife
Subjects:
inner cell mass
trophectoderm
cell fate
preimplantation
cell plasticity
Online Access:https://elifesciences.org/articles/22906

Internet

https://elifesciences.org/articles/22906

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