HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system

HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system

Abstract Despite the effectiveness of combined anti-retroviral therapy, human immunodeficiency virus (HIV) infected-patients frequently report diarrhea and neuropsychological deficits. It is claimed that the viral HIV-1 Trans activating factor (HIV-1 Tat) protein is responsible for both diarrhea and...

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Bibliographic Details
Main Authors: Giuseppe Esposito, Elena Capoccia, Stefano Gigli, Marcella Pesce, Eugenia Bruzzese, Alessandra D’Alessandro, Carla Cirillo, Alessandro di Cerbo, Rosario Cuomo, Luisa Seguella, Luca Steardo, Giovanni Sarnelli
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05245-9

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https://doi.org/10.1038/s41598-017-05245-9

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