Disruption of tumor suppressor gene Hint1 leads to remodeling of the lipid metabolic phenotype of mouse liver[S]

A lipidomic and metabolomic investigation of serum and liver from mice was performed to gain insight into the tumor suppressor gene Hint1. A major reprogramming of lipid homeostasis was found in both serum and liver of Hint1-null (Hint−/−) mice, with significant changes in the levels of many lipid m...

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Bibliographic Details
Main Authors: Diren Beyoğlu, Kristopher W. Krausz, Juliette Martin, Olivier Maurhofer, Juliane Dorow, Uta Ceglarek, Frank J. Gonzalez, Jean-François Dufour, Jeffrey R. Idle
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752034983X