Two Types of PPARγ Ligands Identified in the Extract of <i>Artemisia campestris</i>

Two Types of PPARγ Ligands Identified in the Extract of <i>Artemisia campestris</i>

The 70% ethanol extract of <i>Artemisia campestris</i> was screened to find PPARγ ligands using the PPARγ ligand-responsive chimera luciferase reporter system. Capillartemisin B was identified as a PPARγ ligand that stimulated lipid accumulation in 3T3-L1 cells. By further purification o...

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Bibliographic Details
Main Authors: Tokio Hasegawa, Mayo Osaka, Yusaku Miyamae, Katsutoshi Nishino, Hiroko Isoda, Kiyokazu Kawada, Mohamed Neffati, Kazuhiro Irie, Masaya Nagao
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Chemistry
Subjects:
PPARγ ligand
lipid accumulation
cooperative activation
ligand binding pocket
docking simulation
Online Access:https://www.mdpi.com/2624-8549/3/2/45

Internet

https://www.mdpi.com/2624-8549/3/2/45

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