The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues

The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues

The post-acute phase of SARS-CoV-2 infection was investigated in rhesus (<i>Macaca mulatta</i>) and cynomolgus macaques (<i>Macaca fascicularis</i>). During the acute phase of infection, SARS-CoV-2 was shed via the nose and throat, and viral RNA was occasionally detected in f...

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Bibliographic Details
Main Authors: Kinga P. Böszörményi, Marieke A. Stammes, Zahra C. Fagrouch, Gwendoline Kiemenyi-Kayere, Henk Niphuis, Daniella Mortier, Nikki van Driel, Ivonne Nieuwenhuis, Richard A. W. Vervenne, Tom Haaksma, Boudewijn Ouwerling, Deborah Adema, Roja Fidel Acar, Ella Zuiderwijk-Sick, Lisette Meijer, Petra Mooij, Ed J. Remarque, Herman Oostermeijer, Gerrit Koopman, Alexis C. R. Hoste, Patricia Sastre, Bart L. Haagmans, Ronald E. Bontrop, Jan A. M. Langermans, Willy M. Bogers, Ivanela Kondova, Ernst J. Verschoor, Babs E. Verstrepen
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
SARS-CoV-2
COVID-19
non-human primates
animal models
NHPs
Online Access:https://www.mdpi.com/1999-4915/13/8/1673

Internet

https://www.mdpi.com/1999-4915/13/8/1673

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