The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates

by Jesse Bruijnesteijn, Natasja G. de Groot, Ronald E. Bontrop, Ronald E. Bontrop
Published 2020-09-01

Rapid Characterization of Complex Killer Cell Immunoglobulin-Like Receptor (KIR) Regions Using Cas9 Enrichment and Nanopore Sequencing

by Jesse Bruijnesteijn, Marit van der Wiel, Natasja G. de Groot, Ronald E. Bontrop, Ronald E. Bontrop
Published 2021-09-01

Functional Annotation of Small Noncoding RNAs Target Genes Provides Evidence for a Deregulated Ubiquitin-Proteasome Pathway in Spinocerebellar Ataxia Type 1

by Stephan Persengiev, Ivanela Kondova, Ronald E. Bontrop
Published 2012-01-01

The Impact of MicroRNAs on Brain Aging and Neurodegeneration

by Stephan P. Persengiev, Ivanela I. Kondova, Ronald E. Bontrop
Published 2012-01-01

Insights on the Functional Interactions between miRNAs and Copy Number Variations in the Aging Brain

by Stephan ePersengiev, Ivanela eKondova, Ronald eBontrop
Published 2013-10-01

Extensive Alternative Splicing of KIR Transcripts

by Jesse Bruijnesteijn, Marit K. H. van der Wiel, Nanine de Groot, Nel Otting, Annemiek J. M. de Vos-Rouweler, Neubury M. Lardy, Natasja G. de Groot, Ronald E. Bontrop, Ronald E. Bontrop
Published 2018-12-01

Compound evolutionary history of the rhesus macaque MHC class I B region revealed by microsatellite analysis and localization of retroviral sequences.

by Gaby G M Doxiadis, Corrine M C Heijmans, Maxime Bonhomme, Nel Otting, Brigitte Crouau-Roy, Ronald E Bontrop
Published 2009-01-01

Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evo...

by Christelle Vangenot, José Manuel Nunes, Gaby M. Doxiadis, Estella S. Poloni, Ronald E. Bontrop, Natasja G. de Groot, Alicia Sanchez-Mazas
Published 2020-09-01

Genomic tools for evolution and conservation in the chimpanzee: Pan troglodytes ellioti is a genetically distinct population.

by Rory Bowden, Tammie S MacFie, Simon Myers, Garrett Hellenthal, Eric Nerrienet, Ronald E Bontrop, Colin Freeman, Peter Donnelly, Nicholas I Mundy
Published 2012-01-01

Strong vaccine-induced CD8 T-cell responses have cytolytic function in a chimpanzee clearing HCV infection.

by Babs E Verstrepen, Ernst J Verschoor, Zahra C Fagrouch, Petra Mooij, Natasja G de Groot, Ronald E Bontrop, Willy M Bogers, Jonathan L Heeney, Gerrit Koopman
Published 2014-01-01

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees.

by Babs E Verstrepen, Natasja G de Groot, Zwier M A Groothuismink, Ernst J Verschoor, Rik A de Groen, Willy M Bogers, Harry L A Janssen, Petra Mooij, Ronald E Bontrop, Gerrit Koopman, Andre Boonstra
Published 2012-01-01

The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues

by Kinga P. Böszörményi, Marieke A. Stammes, Zahra C. Fagrouch, Gwendoline Kiemenyi-Kayere, Henk Niphuis, Daniella Mortier, Nikki van Driel, Ivonne Nieuwenhuis, Richard A. W. Vervenne, Tom Haaksma, Boudewijn Ouwerling, Deborah Adema, Roja Fidel Acar, Ella Zuiderwijk-Sick, Lisette Meijer, Petra Mooij, Ed J. Remarque, Herman Oostermeijer, Gerrit Koopman, Alexis C. R. Hoste, Patricia Sastre, Bart L. Haagmans, Ronald E. Bontrop, Jan A. M. Langermans, Willy M. Bogers, Ivanela Kondova, Ernst J. Verschoor, Babs E. Verstrepen
Published 2021-08-01