The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates

by Jesse Bruijnesteijn, Natasja G. de Groot, Ronald E. Bontrop, Ronald E. Bontrop
Published 2020-09-01

Rapid Characterization of Complex Killer Cell Immunoglobulin-Like Receptor (KIR) Regions Using Cas9 Enrichment and Nanopore Sequencing

by Jesse Bruijnesteijn, Marit van der Wiel, Natasja G. de Groot, Ronald E. Bontrop, Ronald E. Bontrop
Published 2021-09-01

Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evo...

by Christelle Vangenot, José Manuel Nunes, Gaby M. Doxiadis, Estella S. Poloni, Ronald E. Bontrop, Natasja G. de Groot, Alicia Sanchez-Mazas
Published 2020-09-01

Humans and Chimpanzees Display Opposite Patterns of Diversity in Arylamine N-Acetyltransferase Genes

by Christelle Vangenot, Pascal Gagneux, Natasja G. de Groot, Adrian Baumeyer, Médéric Mouterde, Brigitte Crouau-Roy, Pierre Darlu, Alicia Sanchez-Mazas, Audrey Sabbagh, Estella S. Poloni
Published 2019-07-01

Strong vaccine-induced CD8 T-cell responses have cytolytic function in a chimpanzee clearing HCV infection.

by Babs E Verstrepen, Ernst J Verschoor, Zahra C Fagrouch, Petra Mooij, Natasja G de Groot, Ronald E Bontrop, Willy M Bogers, Jonathan L Heeney, Gerrit Koopman
Published 2014-01-01

Extensive Alternative Splicing of KIR Transcripts

by Jesse Bruijnesteijn, Marit K. H. van der Wiel, Nanine de Groot, Nel Otting, Annemiek J. M. de Vos-Rouweler, Neubury M. Lardy, Natasja G. de Groot, Ronald E. Bontrop, Ronald E. Bontrop
Published 2018-12-01

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees.

by Babs E Verstrepen, Natasja G de Groot, Zwier M A Groothuismink, Ernst J Verschoor, Rik A de Groen, Willy M Bogers, Harry L A Janssen, Petra Mooij, Ronald E Bontrop, Gerrit Koopman, Andre Boonstra
Published 2012-01-01