Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus

Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus

Zika virus is an emerging arthropod-borne flavivirus for which there are no vaccines or specific therapeutics. We screened a library of 2,000 bioactive compounds for their ability to block Zika virus infection in three distinct cell types with two different strains of Zika virus. Using a microscopy-...

Full description

Bibliographic Details
Main Authors: Keiko Rausch, Brent A. Hackett, Nathan L. Weinbren, Sophia M. Reeder, Yoel Sadovsky, Christopher A. Hunter, David C. Schultz, Carolyn B. Coyne, Sara Cherry
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Cell Reports
Subjects:
antivirals
flavivirus
arbovirus
therapeutics
repurposing
drugs
entry
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716317752

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716317752

Similar Items