Allosteric Antagonism of the A<sub>2A</sub> Adenosine Receptor by a Series of Bitopic Ligands
Allosteric antagonism by bitopic ligands, as reported for many receptors, is a distinct modulatory mechanism. Although several bitopic A<sub>2A</sub> adenosine receptor (A<sub>2A</sub>AR) ligand classes were reported as pharmacological tools, their receptor binding and functi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-05-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/9/5/1200 |