Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy

Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy

Summary: We use super-resolution interferometric photoactivation and localization microscopy (iPALM) and a constrained photoactivatable fluorescent protein integrin fusion to measure the displacement of the head of integrin lymphocyte function-associated 1 (LFA-1) resulting from integrin conformatio...

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Bibliographic Details
Main Authors: Travis I. Moore, Jesse Aaron, Teng-Leong Chew, Timothy A. Springer
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
cell adhesion
cell migration
integrins
super-resolution microscopy
iPALM
immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718301116

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http://www.sciencedirect.com/science/article/pii/S2211124718301116

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