Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women With Alzheimer’s Disease

Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women With Alzheimer’s Disease

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the United States. In spite of evidence of females having a greater lifetime risk of developing Alzheimer’s Disease (AD) and greater apolipoprotein E4-related (APOE ε4) AD risk c...

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Bibliographic Details
Main Authors: Manish D. Paranjpe, Stella Belonwu, Jason K. Wang, Tomiko Oskotsky, Aarzu Gupta, Alice Taubes, Kelly A. Zalocusky, Ishan Paranjpe, Benjamin S. Glicksberg, Yadong Huang, Marina Sirota
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
sex
transcriptomics
biomarker
APOE
inflammation
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.735611/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.735611/full

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