New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches

New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches

FMRFamide-like peptide (FLP) receptors are appealing as putative anthelmintic targets. To date, 31 flp-encoding genes have been identified in Caenorhabditis elegans and thirteen FLP-activated G-protein coupled receptors (FLP-GPCRs) have been reported. The lack of knowledge on FLPs and FLP-GPCRs in p...

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Bibliographic Details
Main Authors: Ciaran J. McCoy, Louise E. Atkinson, Mostafa Zamanian, Paul McVeigh, Tim A. Day, Michael J. Kimber, Nikki J. Marks, Aaron G. Maule, Angela Mousley
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:EuPA Open Proteomics
Subjects:
FMRFamide-like peptide
FLP
FLP-receptor
Neuropeptide GPCR
Nematode
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968514000270

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http://www.sciencedirect.com/science/article/pii/S2212968514000270

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