Protective lipid-lowering variants in healthy older individuals without coronary heart disease

Protective lipid-lowering variants in healthy older individuals without coronary heart disease

Objective Genetic variants that disrupt the function of the PCSK9 (proprotein convertase subtilisin kexin type 9) and APOB (apolipoprotein B)genes result in lower serum low-density lipoprotein cholesterol (LDL-C) levels and subsequently confer protection against coronary heart disease (CHD). The obj...

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Bibliographic Details
Main Authors: Andrew Tonkin, John J McNeil, Sophia Zoungas, Galina Polekhina, Chris Reid, Eric Schadt, Jing Pang, Paul Lacaze, Stephen Nicholls, Jane Tiller, Robert Sebra, Moeen Riaz, Amanda J Hooper, Anne M Murray, Gerald Watts
Format: Article
Language:English
Published: BMJ Publishing Group 2021-08-01
Series:Open Heart
Online Access:https://openheart.bmj.com/content/8/2/e001710.full

Internet

https://openheart.bmj.com/content/8/2/e001710.full

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