A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

Astrocytes can have protective or detrimental effects on neurons during injury, but the molecular mechanisms that determine these different states are unresolved. Here the authors identify a pathway via neuronal EphB1 that induces neuroprotective signalling in astrocytes through ephrin-B1 mediated S...

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Bibliographic Details
Main Authors: Giulia E. Tyzack, Claire E. Hall, Christopher R. Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F. Meyer, Giampietro Schiavo, Su-Chun Zhang, George M. Gibbons, Jia Newcombe, Rickie Patani, András Lakatos
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01283-z

Internet

https://doi.org/10.1038/s41467-017-01283-z

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