C-terminal and full length TDP-43 specie differ according to FTLD-TDP lesion type but not genetic mutation
Abstract The transactive response DNA binding protein of 43 kDa (TDP-43) is an intranuclear protein involved in RNA splicing. Abnormally deposited TDP-43 is found in the brains of patients with frontotemporal lobar degeneration (FTLD). Different morphological characteristics of TDP-43 immunoreactive...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-07-01
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| Series: | Acta Neuropathologica Communications |
| Online Access: | http://link.springer.com/article/10.1186/s40478-019-0755-x |