Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease that can develop therapy resistance over time. The dense stroma in PDAC plays a critical role in tumor progression and resistance. How this stroma interacts with the tumor cells and how this is influenced by chemotherapy re...

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Bibliographic Details
Main Authors: Ashenafi Bulle, Jeroen Dekervel, Lise Deschuttere, David Nittner, Louis Libbrecht, Rekin's Janky, Stéphane Plaisance, Baki Topal, An Coosemans, Diether Lambrechts, Eric Van Cutsem, Chris Verslype, Jos van Pelt
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319305406