Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease that can develop therapy resistance over time. The dense stroma in PDAC plays a critical role in tumor progression and resistance. How this stroma interacts with the tumor cells and how this is influenced by chemotherapy re...
Main Authors: | Ashenafi Bulle, Jeroen Dekervel, Lise Deschuttere, David Nittner, Louis Libbrecht, Rekin's Janky, Stéphane Plaisance, Baki Topal, An Coosemans, Diether Lambrechts, Eric Van Cutsem, Chris Verslype, Jos van Pelt |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-03-01
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Series: | Translational Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523319305406 |
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