RNA Sequencing-Based Identification of Ganglioside GD2-Positive Cancer Phenotype

RNA Sequencing-Based Identification of Ganglioside GD2-Positive Cancer Phenotype

The tumor-associated ganglioside GD2 represents an attractive target for cancer immunotherapy. GD2-positive tumors are more responsive to such targeted therapy, and new methods are needed for the screening of GD2 molecular tumor phenotypes. In this work, we built a gene expression-based binary class...

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Bibliographic Details
Main Authors: Maxim Sorokin, Irina Kholodenko, Daniel Kalinovsky, Tatyana Shamanskaya, Igor Doronin, Dmitry Konovalov, Aleksei Mironov, Denis Kuzmin, Daniil Nikitin, Sergey Deyev, Anton Buzdin, Roman Kholodenko
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomedicines
Subjects:
ganglioside GD2
GD2-positive tumors
neuroblastoma
glioma
immunotherapy
molecular diagnostics
Online Access:https://www.mdpi.com/2227-9059/8/6/142

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https://www.mdpi.com/2227-9059/8/6/142

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