Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial

Abstract Background Colorectal cancer (CRC) is the second most common cause of all cancer deaths in Europe and the Western world with a lifetime risk of approximately 5%. Despite several improvements in the treatment of patients with unresectable CRC prognosis is poor and there is the need of develo...

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Bibliographic Details
Main Authors: Susen Burock, Severin Daum, Ulrich Keilholz, Konrad Neumann, Wolfgang Walther, Ulrike Stein
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4197-9