Brain amyloid and the transition to dementia in Down syndrome

Brain amyloid and the transition to dementia in Down syndrome

Abstract Introduction Down syndrome (DS) is associated with elevated risk for Alzheimer's disease (AD) due to amyloid beta (Aβ) lifelong accumulation. We hypothesized that the spatial distribution of brain Aβ predicts future dementia conversion in individuals with DS. Methods We acquired 18F‐fl...

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Bibliographic Details
Main Authors: David B. Keator, Eric Doran, Lisa Taylor, Michael J. Phelan, Christy Hom, Katherine Tseung, Theo G. M. vanErp, Steven G. Potkin, Adam M. Brickman, Diana H. Rosas, Michael A. Yassa, Wayne Silverman, Ira T. Lott
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's
amyloid
classification
dementia
Down syndrome
positron emission tomography
Online Access:https://doi.org/10.1002/dad2.12126

Internet

https://doi.org/10.1002/dad2.12126

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