Dietary sugars, not lipids, drive hypothalamic inflammation

Dietary sugars, not lipids, drive hypothalamic inflammation

Objective: The hypothalamus of hypercaloric diet-induced obese animals is featured by a significant increase of microglial reactivity and its associated cytokine production. However, the role of dietary components, in particular fat and carbohydrate, with respect to the hypothalamic inflammatory res...

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Bibliographic Details
Main Authors: Yuanqing Gao, Maximilian Bielohuby, Thomas Fleming, Gernot F. Grabner, Ewout Foppen, Wagner Bernhard, Mara Guzmán-Ruiz, Clarita Layritz, Beata Legutko, Erwin Zinser, Cristina García-Cáceres, Ruud M. Buijs, Stephen C. Woods, Andries Kalsbeek, Randy J. Seeley, Peter P. Nawroth, Martin Bidlingmaier, Matthias H. Tschöp, Chun-Xia Yi
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Molecular Metabolism
Subjects:
Microglia
POMC
Obesity
Pericytes
Angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817302399

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http://www.sciencedirect.com/science/article/pii/S2212877817302399

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